B Cells

In lupus, the immune system makes tragic wrong turns, attacking the organs and tissues of the body that it is supposed to defend.

Why does this happen?

What can be done about it?

LRI researchers have bold and out-of-the-box ideas on this.

Stephen H. Clarke, PhD
University of North Carolina at Chapel Hill, NC
Class of 2011

Anne Davidson, MD
Feinstein Medical Research Institute, Manhasset, NY
Class of 2009

Jeffrey Rathmell, PhD
Duke University Medical Center, Durham, NC
Class of 2009

Marko A. Radic, PhD
University of Tennessee, Memphis, TN
Class of 2009
Class of 2015

Changchun Xiao, PhD
Scripps Research Institute, La Jolla, CA
Class of 2009

One possibility: B cells are to blame.

These cells mature in the bone marrow and develop into cells that make antibodies when stimulated.

Jennifer Anolik, MD, PhD
University of Rochester, NY
Class of 2007

Randall Davis, MD
University of Alabama at Birmingham, AL
Class of 2013

Betty Diamond, MD
Feinstein Institute for Medical Research, North Shore-LIJ Health System
Class of 2014

Loren Erickson, PhD
University of Virginia, VA
Class of 2007

Edmund J. Gosselin, PhD
Albany Medical College, Albany, NY
Class of 2001

Thereza Imanishi-Kari, PhD
Tufts University School of Medicine, Boston, MA
Class of 2006

William Kovacs, MD
Pennsylvania State University College of Medicine
2012 B Cells

Amy S. Major, PhD
Vanderbilt University School of Medicine, Nashville, TN
Class of 2014

Roberta Pelanda, PhD
National Jewish Health, Denver, CO
Class of 2013


Yufeng Peng, PhD
University of Washington, Seattle, WA
Class of 2012


Hidde Ploegh, PhD
Whitehead Institute for Biomedical Research, Cambridge, MA
Class of 2008

Eline Luning Prak, MD, PhD
University of Pennsylvania, Philadelphia, PA
Class of 2012

Thomas Rothstein, MD, PhD
The Feinstein Institute for Medical Research, NY
Class of 2007
Class of 2012

Alexander Tarakhovsky, MD, PhD
The Rockefeller University, NY
Class of 2012

Matthias Wabl, PhD
University of California, San Francisco, CA
Class of 2012

Martin Weigert, PhD
University of Chicago, IL
Class of 2001

Barbara J. Vilen, PhD
University of North Carolina at Chapel Hill, NC
Class of 2001