2007 B Cells
Over the past few years, evidence has been growing that B cells (B lymphocytes) play a central role in the cause and development of lupus by making antibodies to the body’s own DNA.
Consequently, therapies that eliminate B cells are of great interest, and a number of clinical trials that test this concept in people with lupus are currently underway.
Dr. Anolik will develop a mouse model to study the why depleting B cells like this successfully counters lupus in some people.
The hope: that greater understanding of this link may lead to more effective treatments for lupus.